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Re: Going to try ginkgo + melatonin combination

Posted by linkadge on April 15, 2005, at 18:53:50

In reply to Re: Going to try ginkgo + melatonin combination, posted by LOOPS on April 15, 2005, at 13:08:43

Interstingly enough, ginkgo alone does have an effect on improving sleep archetecture. Perhaps due to its neuroendocrine effects.

The real key effect I am trying to get here is maximal 5-ht1a activation. Many doctors believe that the key effects of serotogenic medications are through activation of the 5-ht1a receptors.

Melatonin increases 5-ht1a receptor responsivness, and ginkgo acts as a fairly potent 5-ht1a agonist.

The first time I tried gingko, (before using any antidepressants) I noticed two things.

Less daytime anxiety (adrenaline surges,
worrying etc)

Better sleep.


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URL: http://www.dr-bob.org/babble/alter/20050414/msgs/484839.html