Posted by tealady on December 6, 2003, at 18:28:15
In reply to Re: back on tyrosine: » tealady, posted by JLx on December 1, 2003, at 8:22:13
Hi,
Just some links that may provide some help with things we've been discussing.
http://forums.about.com/ab-thyroid/messages?msg=51604.209 magnesium
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?tool=bookshelf&call=bv.View..ShowSection&searchterm=selenium&rid=bnchm.section.2391#2401
Nutrition and Functional Neurochemistrycortisol stuff..the blind leading the blind , but you may get some ideas
http://forums.about.com/n/mb/message.asp?webtag=ab-thyroid&msg=53370.1http://forums.about.com/n/mb/message.asp?webtag=ab-thyroid&msg=52997.1
http://forums.about.com/ab-thyroid/messages?msg=51604.195
http://forums.about.com/ab-thyroid/messages?msg=46319.609 xmas joke
http://forums.about.com/ab-thyroid/messages?msg=46319.567 joke
http://forums.about.com/ab-thyroid/messages?msg=51604.158 vitD..may be relevant to your calcium balance problem..click on links in post
Not sure if below is relevant to you or not? (only have access to abstract)..you seem to need an extra large dose of magnesium compared o most people
Hormone-stimulated Mg(2+) accumulation into rat hepatocytes: a pathway for rapid Mg(2+) and Ca(2+) redistribution.
Fagan TE, Scarpa A.
School of Medicine, Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA.
Many diseases such as cardiac arrhythmia, diabetes, and chronic alcoholism are associated with a marked decrease of plasma and parenchymal Mg(2+), and Mg(2+) administration is routinely used therapeutically. This study uses isolated rat hepatocytes to ascertain if and under which conditions increases in extracellular Mg(2+) result in an increase in intracellular Mg(2+). In the absence of stimulation, changing extracellular Mg(2+) had no effect on total cellular Mg(2+) content. By contrast, carbachol or vasopressin administration promoted an accumulation of Mg(2+) that increased cellular Mg(2+) content by 13.2 and 11.8%, respectively, and stimulated Mg(2+) uptake was unaffected by the absence of extracellular Ca(2+). Mg(2+) efflux resulting from stimulation of alpha- or beta-adrenergic receptors operated with a Mg(2+):Ca(2+) exchange ratio of 1. These data indicate that cellular Mg(2+) uptake can occur rapidly and in large amounts, through a process distinct from Mg(2+) release, but operating only upon specific hormonal stimulation. (c) 2002 Elsevier Science (USA).
PMID: 12054479 [PubMed - indexed for MEDLINE]
carbachol
<drug> Parasympathomimetic drug formed by substituting the acetyl of acetylcholine with a carbamyl group, acts on both muscarinic and nicotinic receptors and is not hydrolysed by acetylcholine esterase.vasopressin
<protein> A peptide hormone released from the posterior pituitary lobe but synthesised in the hypothalamus. There are 2 forms, differing only in the amino acid at position 8: arginine vasopressin is widespread, while lysine vasopressin is found in pigs. Has antidiuretic and vasopressor actions. Used in the treatment of diabetes insipidus.vasopressor
1. Stimulating contraction of the muscular tissue of the capillaries and arteries.2. An agent that stimulates contraction of the muscular tissue of the capillaries and arteries.
arginine
<amino acid> An essential amino acid, a major component of proteins and contains the guanido group that has a pKa of greater than 12, so that it carries a permanent positive charge at physiological pH. It becomes an essential amino acid when the body is under stress or is in an injured state.Depressed growth results from lack of dietary arginine. Arginine deficiency syndrome is observed in human babies born with a phosphate synthetase deficiency. Normal growth and development in these infants are achieved by adding arginine to their diet. Arginine deficiency leads to carbamyl phosphate overproduction in the mitochondria due to inadequate ornithine supply. Arginine-deficient diets in males causes decreased sperm counts. Free and bound arginine are found in abundance in human male sperm and arginine has been found to stimulate sperm motility.
There are two sources of arginine, arginine in the food chain and free-form arginine from supplements. Food-source arginine is found in abundance in turkey, chicken and other meats. Nonfood-source arginine is called L-arginine and is created through a fermentation process which separates arginine from all other proteins. In the presence of food and other amino acids, L-arginine will act like food-source arginine but when L-arginine is separated from its nutrient boundaries by the removal of all other amino acids, then L-arginine undertakes a different role, becoming capable of crossing the blood-brain barrier and stimulating growth hormone release secreted by the anterior pituitary.
Growth hormone serum levels peak during adolescence and begin to drop after age 23. Aging reduces natural growth hormone production, which results in added body fat, reduced muscle tissue, slowed healing, lack of elasticity in the skin and reduced immune function. Human pituitary growth hormone secretion is evidenced in human males, females and children following intravenous administration of 30 grams of arginine (in 30 minutes) in adults and 0.5 grams/kilogram of bodyweight in children. Female response is somewhat higher than male response. Oral administration of L-arginine also results in the release of Human Growth Hormone.
Tumour suppression is evidenced in the presence of L-arginine. In the Barbul study, tumours recurred in 100% of the control animals. But in the arginine-supplemented group, only about 60% of the tumours recurred and the animals with tumours survived longer. Supplementation of arginine in the diet inhibits development and increase in size of cancerous tumours, both chemically induced and naturally occurring.
Insulin can block growth hormone release, so high serum insulin levels are counterproductive to GH release. Insulin itself is capable of stimulating muscle growth, but it also strongly stimulates fat storage. Muscle growth stimulation from insulin is minuscule compared to muscle growth stimulated by growth hormone.
(13 Nov 1997)
Jan
PS.
Brain fog..or bad short term memory is a symptom of hypothyroid..and one that is a bit too touchy at present for me. I'm like you, I need to retrain in something and get back into the workforce, sigh.
I'm not sure if I'll be around much longer, my babble mail is on.
poster:tealady
thread:283253
URL: http://www.dr-bob.org/babble/alter/20031204/msgs/287240.html