Posted by DSCH on September 15, 2003, at 8:23:56
In reply to Re: Update time :-) (Redirect Dr. Bob? Meds!) » DSCH, posted by francesco on September 15, 2003, at 2:49:59
OK, that sounds more serious than was my original impression. Sounds like a focused form of impulsiveness to me (somewhat paradoxical), and increased agression, lowered empathy. Not really OCD or SP or BP. More like one of the personality/mood disorders... like oppositional/defiant (ODD)? (Euro description: http://www.mentalhealth.com/icd/p22-ch05.html )
The thing that strikes me about clomipramine (Anafranil) is its strong serotonin reuptake inhibition and its antagonism for NE-alpha receptors. To me, having NE reuptake inhibition and then antagonizing some of the NE receptors sounds like "one step forward, one step back" but I am not familar with the actions of each NE receptor type (some could be down-regulators).
I would think that of the other "+++ meds" for ADHD from the Italian viewpoint, the TCs imipramine and nortriptyline would do for you much as clomipramine, a TC itself, has done. Guanfacine I don't know anything about. Clonidine, which SLS lists as a NE-alpha2 agonist sounds like it might be helpful in your case.
poster:DSCH
thread:257359
URL: http://www.dr-bob.org/babble/alter/20030903/msgs/260178.html