Posted by pedr on May 24, 2024, at 7:46:26
👋 Hi folks,
I am happy to see some of the old hands are still here and that this server is (just about) still kicking :) - PeterMartin, SLS, Hugh, Roslynn, Lamdage22 - and sorry to those Ive not mentioned/forgotten (the ol ECT, depression and the mountains of anti-depressants dont help with recall I find).
This is my first post in many a year and Ill say up front, with my treatment-resistant {Depression,OCD,ADHD}, please dont be put out if I dont reply promptly. Writing anything is often very, very difficult.
Enough bluster already, rando guy! - to my point: I recently reached the 12 month mark of VNS (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990624/) without responding, which meant that yet another treatment had failed me and my PDoc who was managing the VNS said Have you tried Auvelity? I hadnt, and now I have, and after 3-4 days, my World expanded and some light was shone into it. It was surreal.
However (theres always a however, isnt there?), I am now 14 days in and am experiencing some of the most intense exhaustion/somnolence/spotaneous sleeping Ive ever experienced - AND IVE BEEN ON NARDIL!!! /j
Basically, I know that a bunch of you are some of the smartest cookies on tinternets about drug cocktails, their SEs and the like and I thought Id see if anyone can spot any likely candidate interactions/? that might be behind this crushing exhaustion (I am squinting *incredibly hard* just to be able to see the text Im typing). So heres my regimen. Its a big one, inflated by pain management meds for spine surgery last year :
- 25 Lexapro,
- ad-hoc 100mg provigil,
- 15 Buspar
- ~60mg Oxycodone
- 2.5 Abilify
- 2mg Lorazepam
- 600 Lyrica
- ~100 Ritalin
- 100-150 Trazodone (usually I cannot sleep and this helps best of anything Ive tried)
- Auvelity
- Fetzima 40mg
- Baclofen (I thought this was the cause but Ive trialled skipping it and the somnolence is unchanged)
- 2400mg Ibuprofen (Surgeon prescribed)
- 20mg Omeprazole (for NERD)Oh, also, if anyone knows any good Auvelity forums where I could also ask about this bonkers exhaustion, I would be violently appreciative 🙏🏻
Pedr
TRD, TR OCD since 1996.
Meds: 40 Fetzima, 30 Lexapro, 30 Ritalin, 60 Adderall, 2.5 Abilify, 45 Buspar (OCD/GAD), 300 Lyrica, 150 Trazodone (sleep), 40 Percocet (Chronic Pain)
Ad hoc: 2 Ativan
poster:pedr
thread:1122375
URL: http://www.dr-bob.org/babble/20230117/msgs/1122375.html