Posted by SLS on February 25, 2023, at 12:10:24
In reply to Another review on lithium and renal impairment, posted by undopaminergic on February 25, 2023, at 11:02:10
One way to mitigate the stress on the kidneys produced by lithium is to take the entire dosage once at night.
Kidney effects with lithium are dosage-dependent.
To treat depression when there is no history of mania, hypomania, or rapid-cyclicity, low-dosage lithium therapy (150-450 mg/day) might be ideal. I don't know if the rate of response for unipolar depression is any different than for bipolar depression. Lithium augmentation of tricyclic and SSRI antidepressant treatments haves been studied since the 1970s. It has the longest history of demonstrating its effectiveness in both unipolar and bipolar depressions. However, I wouldn't be surprised if low-dosage lithium treatment were more effective for bipolar depression than for unipolar depression, but that's just a guess.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1121859
URL: http://www.dr-bob.org/babble/20230117/msgs/1121862.html