Posted by undopaminergic on February 12, 2023, at 12:00:25
In reply to Re:Neuroleptics brain specific antihistaminergic? » undopaminergic, posted by Jay2112 on February 9, 2023, at 19:10:51
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> > > > > I found something that you might find useful:
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> > > > > https://pubmed.ncbi.nlm.nih.gov/20021346/
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> > > > I'm very interested in trying a histamine H3-receptor antagonist (or inverse agonist), but none are clinically available.
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> > > > -undopaminergic
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> > > Do you know whether or not any H3 antagonists are in the pipeline for FDA approval?
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> > No, I don't know. But I was wrong: betahistine is mostly a histamine H3-receptor antagonist, and it is clinically available in Europe, including my location, but it was withdrawn from the market in the US.
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> > -undopaminergic
> >
>
> I took betahistine for almost 3 months (I am in Canada). It seemed to make me very depressed. I was taking it for inner-ear problems.
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> JayH3 antagonists increase histaminergic neurotransmission, and should have stimulant-like effects. Maybe you have endogenously high histamine? Do you benefit from regular (H1) antihistamines?
-undopaminergic
poster:undopaminergic
thread:1121718
URL: http://www.dr-bob.org/babble/20230117/msgs/1121771.html