I was thinking about Beckett2's case earlier today, and I played out a hunch. I recall a paper I read long ago that described an interaction between magnesium and glutamate at the NMDA receptor. Somehow, the magnesium facilitated a greater degree of receptor antagonism demonstrated by ketamine.
I like puzzles.
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"Combination of ketamine and magnesium in a normal magnesium level presents a superadditive effect in depression treatment."
https://pubmed.ncbi.nlm.nih.gov/31488789/
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- Scott
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this signature | Show by default | Change to hide (next time)Some see things as they are and ask why.
I dream of things that never were and ask why not.
The only thing necessary for the triumph of evil is that good men do nothing.