Posted by SLS on November 9, 2022, at 22:13:02
In reply to Re: More taychcardia on atomoxetine than Ritalin, posted by linkadge on November 9, 2022, at 10:16:05
> But, norepinephrine is a 'stimulating' brain chemical. For example, atomoxetine has been used in chronic fatigue and depression related fatigue with success. This is why drugs like venlafaxine and desipramine are more 'stimulating' than SSRIs. If it's stimulating, then isn't it a stimulant?
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> Linkadge
It might be more accurate to view the amine neurotransmitters as being neuromodulators. Neurons are cables that send messages. Glutamate and aspartate are the stimulatory neurotransmitters. Glycine and GABA are inhibitory. These chemicals either facilitate or they block the messages (action potential) being sent to a destination along a network of circuits. The circuitry is the brain, not the amine modulators (dopamine, norepinephrine, serotonin, trace amines, and myriad other substances). These are not the messengers, but are more like amplifiers and suppressors of the sub-circuits.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1120972
URL: http://www.dr-bob.org/babble/20220917/msgs/1120993.html