Posted by linkadge on August 30, 2022, at 6:16:24
In reply to Re: Day 4 - darker mood - palpations, posted by undopaminergic on August 30, 2022, at 3:49:43
>Pramipexole did the opposite for me. Colours were more vivid and music sounded wonderful. I wonder why's that if both are pro-dopaminergic substances.
Yeah, that is very interesting. Another conundrum is the fact the pramipexole is linked to compulsive disorders, whereas bupropion can be used to reduce addictive behaviours (smoking, gambling etc).
I wonder if there is a link between the two. Seriously, casinos use bright vivid shiny colors to increase gambling. Perhaps pramipexole activates certain pathways that intensify this reward related anticipation (and accompanying perceptual intensification related reward). Conversely, bupropion (somehow) blocks these pathways, and hence reduces addictive behaviours.
Bupropion is linked to a lower rate of mania induction than other antidepressants. This doesn't really jibe with its on-paper targets. There must be other things going on with this med.
Linkadge
poster:linkadge
thread:1120496
URL: http://www.dr-bob.org/babble/20220530/msgs/1120552.html