Posted by undopaminergic on August 30, 2022, at 4:05:19
In reply to Re: Low dose aspirin for depression or BPDepression? » undopaminergic, posted by linkadge on August 29, 2022, at 12:54:02
> >You can't go beyond 100% MAO inhibition, so >theoretically, there is no particular risk.
>
> Hmm. I thought it was possible to get serotonin syndrome from combinations of MAOIs. I was under the impression that MAOIs were typically not combined for this reason.
>
> LinkadgeIt is possible that some MAOIs have serotonergic activity beyond MAO inhibition. For example, the amphetaminergic action of tranylcypromine (Parnate) might cause the release of some serotonin.
However, as I said, you can't go beyond 100% MAO inhibition, so combining two (pure) MAOIs should have no effect beyond a larger dose of only one of them.
-undopaminergic
poster:undopaminergic
thread:1120514
URL: http://www.dr-bob.org/babble/20220530/msgs/1120549.html