Another interesting combination treatment.

Posted by SLS on August 25, 2022, at 13:45:06

Hi.
"The effect of bupropion augmentation of minocycline in the treatment of depression"
https://pubmed.ncbi.nlm.nih.gov/31342957/

Minocycline is an antibiotic that also reduces inflammation in the brain. It accomplishes this through suppressing the secretion of pro-inflammatory cytokines from microglial cells. Of course, it might do other thing. Minocycline does have significant antidepressant effects. It helped me for quite some time. However, I had to discontinue it because hyperpigmentation of the skin appeared on my feet and lower legs. This side effect didn't emerge until I had taken minocycline for almost a year.
I haven't a clue as to how bupropion and minocycline might have a synergistic effect.

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
The only thing necessary for the triumph of evil is that good men do nothing.

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Another interesting combination treatment. SLS 8/25/22
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