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Re: Amur Corktree arrived » SLS

Posted by Jay2112 on July 24, 2022, at 23:49:53

In reply to Re: Amur Corktree arrived, posted by SLS on July 23, 2022, at 8:35:37

> > Why would certain MAO-B inhibitors feel different than others?
>
> That's a great question. The answer to that question relies on uncertainty I think we have seen enough counterintuitive responses to drugs on this board. Eventually, what we consider counterintuitive today will be easily explainable in the future as more information is gathered.
>
> In my estimation, a robust response to an MAOI depends the inhibition of MAO-A. The package label for EMSAM explains this explicitly. However, a MAO-B inhibitor called pargyline was used to treat depression for many years before it was withdrawn from market. Nothing was wrong with the drug other than its waning popularity.
>
>
> - Scottt

Hi Scott,

Is pargyline not similar to that drug you said was the worlds 'best' antidepressant? It had a huge success rate, but was taken off the market due to cardiac issues?

Jay


Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-


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poster:Jay2112 thread:1120116
URL: http://www.dr-bob.org/babble/20220530/msgs/1120142.html