Posted by SLS on April 18, 2022, at 23:38:23
In reply to Re: 'anything can happen with psych drugs...' » SLS, posted by undopaminergic on April 18, 2022, at 10:06:58
> >
> > Protriptyline exacerbated my depression tremendously. I don't know why (of course). If I recall properly, it is biased towards blocking norepinephrine reuptake.> Like nortriptyline?
I really can't say. It think protriptyline might exert both NE reuptake inhibition and a strong anticholinergic effect. I have a tendency to focus on dopamine as being the common denominator in my case.
> > Reboxetine made my depression much worses. It's selective for inhibiting NE reuptake, I believe.>
> It is. It relieved my emotional issues, by worsening my depersonalisation/derealisation, ie. it numbed my emotions. Permanently.I am profoundly sad to know this. The risk we take with antidepressants is a reflection of how little we understand. In order to treat everyone effectively, we need to think of each brain as having a unique topography that must be mapped before choosing a path to follow.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1119379
URL: http://www.dr-bob.org/babble/20220128/msgs/1119427.html