Posted by Christ_empowered on April 18, 2022, at 17:04:08
In reply to Re: nuerontin's antidepressant effects, posted by rjlockhart37 on April 18, 2022, at 13:30:19
i often wonder how many psych problems could be (and are, probably) improved if someone would just developer safer, easy to tolerate sedatives.
in some old drug ads..."whatever the diagnosis, LIBRIUM." because...yeah...everyone, from moody teenagers to angry manic depressives, could use a Librium. I...agree with that, actually. :-)
apparently, just about any substance that reduces anxiety and tension can result in "improvement" on various depression scales. That's part of why Seroquel can "improve depression" in some small studies even with incredibly low doses (read: more antihistamine than cns drug at those doses...).
benzodiazepines, too, can help. and neurontin, for some (many?) people. and...
Ever taken ashwagandha? I do, now...Jarrow brand, so far so good. Its been tested at higher doses for adjunctive use in stable, medicated people with long term Schizophrenia who are showing signs of relapse (I think back in the day they would call that "acute exacerbation of Schizophrenia" and/or "the prodromal phase" or...something, I dunno...). kind of...a very select patient group, I think, but...
yeah, it helps. or it seems to, in that small study. and its non-toxic, I don't think there's a discontinuation syndrome, and..yeah. yeah. I think it may have some antioxidant effects, so one could argue for it being relatively inexpensive, readily available, safe, and potentially beneficial in some respects, on top of the psych stuff.
so, yeah. in that small study, a lot of the stable (but approaching..instability?!?) people were able to keep on keepin' on and improve -negative symptoms- (I find that interesting...to me, those overlap with depression, and neuroleptics seem to exacerbate them, in a lot of people...), and the neuroleptic dosage stayed steady, which is an excellent thing for long-term health and such.
ok. I don't care much for gabapentin, personally. I seem to somehow...get more -obvious- cognitive impairment than I was expecting, and my mood is sometimes brighter, but less...even. not that I go crazy, just...ugh. -next Rx, please...- it happens.
thanks for the post. :-)
poster:Christ_empowered
thread:1119403
URL: http://www.dr-bob.org/babble/20220128/msgs/1119411.html