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Re: Low dose venlafaxine basically an SSRI?

Posted by NKP on August 10, 2021, at 5:33:56

In reply to Re: Low dose venlafaxine basically an SSRI?, posted by linkadge on August 9, 2021, at 15:51:48

> It doesn't really make sense to have an SSRI with the side effects of an SNRI. If it has side effects consistent with an SNRI then it must have some effects on norepinephrine.
>
> On paper, venlafaxine's occupancy of the norepinephrine transporter is lowish. However, PET studies have shown much higher occupancy than you'd expect.
>
> https://pubmed.ncbi.nlm.nih.gov/23090625/
>
> https://pubmed.ncbi.nlm.nih.gov/18418363/
>
> https://pubmed.ncbi.nlm.nih.gov/30649319/
>
> Linkadge

Thank you for this information. That is very interesting.


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