Posted by SLS on August 6, 2021, at 2:09:46
In reply to Re: Which antidepressants are 'less' activating?, posted by linkadge on August 5, 2021, at 19:37:01
When Prozac and Zoloft had just come out, my archaic way of thinking was that the TCAs would show better than the SSRIs. My doctor did not agree. At this point, I can't cite anything that seperates these classes of drugs as far as side effects are concerned. As was mentioned, clomipramine (Anafrinil) has the reputation as having the most potent TCA. It will get more people well than does imipramine or amitriptyline. Clomipramine is definitely NOT less effective than the SSRIs. Many studies show they are equivalent or superior. In my experience, nortriptyline and trimipramine are the mildest of the TCAs that still work. Sleeplessness is probably the worst aspect of desipramine. Nortriptyline is my current best TCA.
- Scott
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> More sedating antidepressants may include:
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> fluvoxamine
> paxil
> trazodone
> mirtazapine
> amitriptyline
> trimipramine
> doxepin
> clomipramine (look into this one)
> amoxapine
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> Don't write off the TCAs. I found them much more tolerable (and effective) than the SSRIs. On paper (for instance) nortriptyline is supposed to be activating, but I found it much less activating than something like zoloft.
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> Linkadge
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Some see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1116258
URL: http://www.dr-bob.org/babble/20210723/msgs/1116275.html