> Does increasing GABAergic neurotransmission lessen psychotic symptoms?
There have been studies which suggest a co-relation. Just go to pubmed and search. GABA seems to fall with an increase in l-arginine in psychosis. As well, GABA is decreased by an increase in NDMA agonism associated with an increase in l-glutamine.
Regular "GABA" you find in health food stores does not cross the blood-brain barrier. Lyrica (pregablin) and Neurontin (gabapentin) do, put I am not sure about their use in preventing or treating psychosis. Depakote/Epival also has a pro-GABA effect, and all of those meds are used highly in Bipolar, and quite effective in reducing agitation and mania.
Jay
![[collapse]](http://www.dr-bob.org/images/babble/hide.gif)
this signature | Show by default | Change to hide (next time)Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-