Posted by SLS on March 6, 2021, at 11:52:30
In reply to Re: mood stablizers, posted by undopaminergic on February 24, 2021, at 2:02:27
> >
> > does anyone know if mood stablizer can be used for depression alone?
>
> Yes, for a lot of psychiatrists that is the first option for bipolar disorder.
>
> -undopaminergic
>Maybe Lamictal (lamotrigine). My guess is that it increases dopamine activity in the nucleus accumbens via disinhibition facilitated by a reduction of glutamate release in the thalamus. There may be other structures involved as well.
I would like to mention that an apparently unipolar depression can still have a bipolar diathesis. This alone warrants a trial of a mood stabilizer when antidepressants alone do not have much, if any, appreciable effect.
Oxcarbazepine, tiagabine, and lamotrigine would my picks.
- Scott
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poster:SLS
thread:1113858
URL: http://www.dr-bob.org/babble/20210120/msgs/1113982.html