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Re: Rexulti

Posted by Christ_empowered on November 2, 2020, at 11:22:49

In reply to Re: Rexulti, posted by undopaminergic on October 31, 2020, at 3:51:51

unless the issue at hand is psychotic depression or depression with -significant- agitation, i don't see the justification for a neuroleptic. from what i've skimmed over on the data for aripiprazole, the aggregate shows a minor drop in misery scores, no indication of improvement in quality of life or anything...anything that would justify the risks and expen$e.

if the main issue is Bipolar I, then maybe a neuroleptic is acceptable? even then, the traditional treatment protocols called for minimizing exposure to neuroleptics in Bipolar I when possible, because Bipolar I people are apparently more prone to EPS, more likely to develop TD, and the TD in this group of people is more likely to be on the severe end vs those with a diagnosis of Schizophrenia. but that could just be more psych 'wisdom' that is/was based on assumptions, dogma, and low quality data. who knows? not me...

have you (or whomever the question is about...) given aripiprazole a trial? I take it, daily. ugh. its...OK. for my "condition," a neuroleptic is usually standard, so its more a question of dosage, which tranquilizer, and what if any additional psych drugs are needed, etc.

from what -very- little 'expert' opinion i've read on the issue, it would appear that aripiprazole is a better 1st option, -if- a neuroleptic is needed. the data isn't there to justify the additional costs and still largely unknown risks with the newer me-too drugs.

and...im finished. lol. hope this helps. :-)


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