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Re: Anxiolysis does not need to be addictive undopaminergic

Posted by linkadge on October 11, 2020, at 7:48:52

In reply to Re: Anxiolysis does not need to be addictive, posted by undopaminergic on October 11, 2020, at 1:29:38

This is true. Some studies show that there are structural improvements (i.e. hippocampal volume) with traditional antidepressants, over time. They can also be neuroprotective. I don't know if the same can be said for stimulants.

Ketamine seems to have a mixture of neurotrophic effects and immediate activation of reward systems. Who knows the relative contribution of these two. However, I would say that (on average) a single dose of ketamine would last longer than a single dose of a stimulant or opioid (for most depressed patients). So, there is something more going on here than simply activating your reward system.

Linkadge


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