Nortriptyline or desipramine

Posted by JFL on September 27, 2020, at 8:38:04

After having tried a few SSRIs, SNRIs, ECT, mirtazapine with Wellbutrin, and Nardil, my psychopharmacologist has recommended that I try a tricyclic: either nortriptyline or desipramine.
I suffer from unipolar depression, along with anxiety.
The thought of going on a tricyclic makes me very anxious, due to the potential side effects. Which of these two medicines has a more likely chance of fewer side effects? Which would be more effective?
I am currently on 90 mg mirtazapine, 450 mg Wellbutrin, 200 mg Lamictal, 5 mg Abilify, 1200 mg gabapentin, and 2 mg clonazepam.

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Nortriptyline or desipramine JFL 9/27/20
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