Psycho-Babble Medication | about biological treatments | Framed
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Re: Nardil/ Phenelzine dosing schedule

Posted by linkadge on August 29, 2020, at 12:32:38

In reply to Nardil/ Phenelzine dosing schedule, posted by Stargazer2 on August 29, 2020, at 9:15:32

Hmm. Wikipedia says 11.6 hours. Some of it may depend on individual metabolic differences.

One thing to keep in mind is that, the biological effect of phenelzine will last much longer than the half life of the drug itself. Because phenelzine 'irreversibly' binds to MAO, the MAO action will last as long as it takes for your brain to synthesize new MAO (typically a few weeks).

This is why (despite a short half life), they say you need to stop Nardil for at least 2 weeks before starting an SSRI.





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