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Re: how long does lithium take effect

Posted by SLS on August 27, 2020, at 23:55:12

In reply to Re: how long does lithium take effect rjlockhart37, posted by stargazer2 on August 27, 2020, at 0:37:08

> For me lithium seems to kick in right away. I take 300 ER only 1x/wk and I said to my new doc it works but she wanted me to Increase it to every day. Every doc wants to change the formula that works even though they dont understand why it works. So I started with every other day and it made me so tired I knew it was too much. Maybe I just need the lowest dose of the Immediate release which would be 100mg.
> I am ultra sensitive to most meds but that hit me pretty hard. Then I tried to go up to 300 every day before my MD appt to meet her expectations and I had troubling talking. Now Im back but taking maybe 2-3x/wk to just have a higher dose in my system w/o side effects.
> I think Ill go down to 100 though. My call as I know how I feel, docs never will in psychiatry.
>

For me, lithium improves depression at low dosages and exacerbates it at high dosages. I ran across a paper describing a biphasic effect of lithium on glutamate:

1. Low dosage = increased glutamate activity = antidepressant?
2. High dosage = decreased glutamate activity = antimanic?


Lithium does so many things, its hard to keep up with.

Antidepressant.
Anti-suicide.
Anti-manic.
Anti-Alzheimer's Dementia.
Anti-brain cancer.
Prevent or improve the outcome of radiation treatment on brain tumors.
Increase BDNF.


Linkadge should be able to put together a longer list of uses for lithium.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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