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Re: Dopamine agonists and antagonists...used together?

Posted by undopaminergic on August 16, 2020, at 4:28:24

In reply to Re: Dopamine agonists and antagonists...used together?, posted by SLS on August 15, 2020, at 13:32:44

> > > I'm just wondering if there are instances where dopamine agonists and antagonists might be used together in psychiatry? Mainly, I'm wondering if the blunted effect one might get from DA antagonists might be helped by adding in a DA agonist.
> > >
> >
> > Yes, but it is pretty rare. When an agonist is added, it may be necessary to increase the dose of the antagonist, if there is an increase in "positive" symptoms (ie. psychosis).
> >
> > -undopaminergic
> I think a partial DA agonist might be a better way to go.
> Vraylar; Abilify; Rexulti

It's worth a try. But they won't substitute for something more potent, such as dextroamphetamine, which among other things can improve working memory.





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