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Re: Carbidopa or Carbidopa + Levodopa + depression

Posted by undopaminergic on August 7, 2020, at 0:25:36

In reply to Carbidopa or Carbidopa + Levodopa + depression, posted by MightyKondrian on August 6, 2020, at 19:17:00

> I'm curious about the effects of adding either Carbidopa, L-dopa or a combination of both to an irreversible MAOI. In my case isocarboxazid.
>
> There is some information floating around the net but nothing that really answers my question, so I came here.
>
> Does anyone here have any thoughts about adding Carbidopa, L-dopa or a combination of both to an MAOI that has been taken continuously for over a year?
>
> Anyone even experimented with these, not including those with pre-existing Parkinson's? I'm thinking probably not.
>

I would not expect carbidopa to have much effect on its own. Taken with L-dopa and under MAO inhibition, it could potentially have powerful effects, and I would advise caution.

That said, L-dopa didn't work for me, even with benserazide (an alternative to carbidopa).

-undopaminergic


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