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Re: Brain's Opioid System Linked to Depression/Anxiety

Posted by Hugh on June 24, 2020, at 12:58:13

In reply to Brain's Opioid System Linked to Depression/Anxiety, posted by Hugh on June 21, 2020, at 15:46:31

Taking a low dose of naltrexone daily helps to boost the amount of natural opiates your brain produces. I've taken low-dose naltrexone (LDN) for years, and I've tried many different doses -- all the way up to what is considered to be LDN's maximum dose of 4.5 mg. And I've experimented with ultra-low-dose naltrexone (ULDN), taking doses in the micrograms, nanograms, and picograms.

Naltrexone is water-soluble, so I dissolve a 50-mg tablet in 50 ml of distilled water and keep it in the refrigerator. I use a medicine dropper to measure the dose. Most people take LDN at bedtime.

Of all the many different doses of naltrexone I've tried, the ones that have had the most positive effect on my mood were 125 mcg and 250 mcg. But every brain is different.

This thread discusses LDN and ULDN:




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