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Re: Escitalopram vs Sertraline

Posted by undopaminergic on May 4, 2020, at 10:56:05

In reply to Escitalopram vs Sertraline, posted by Skeletor on May 4, 2020, at 8:19:38

> Both are second-generation SSRIs, both exhibit minimal drug interactions via Cytochrome P450, both are the most prescribed SSRIs and are considered first line antidepressants. Who's been taking both and what were your experiences? (How did they compare to each other?). I am looking forward to read your experiences...
>
> Which one did you like more?

Sertraline seemed most potent, but not per mg. Thus it had stronger adverse effects, including apathy and prolonging time to orgasm. I did alas not notice its dopaminergic effects at higher doses.

So if you think you benefit from stronger serotonergic effects, go for sertraline.

Somewhat interestingly, I found that it reduces the risk of suicide because it makes you apathetic enough not to take action on your suicidal ideas. You're more likely to just stay in bed.

-undopaminergic


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poster:undopaminergic thread:1109958
URL: http://www.dr-bob.org/babble/20200303/msgs/1109959.html