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Re: Thyroid NET and DAT

Posted by undopaminergic on April 5, 2020, at 11:53:53

In reply to Thyroid NET and DAT, posted by linkadge on April 4, 2020, at 8:18:54

> Thyroid acts as a specific norepinephrine and dopamine reuptake inhibitor:
>
> https://www.ncbi.nlm.nih.gov/pubmed/17530732
>
> Linkadge

My understanding of the abstract is that there are metabolites of thyroid hormones, called thyronamines, that act as inhibitors of NAT, and DAT, and they also inhibit vesicular monoamine uptake, apparently via agonism at the TAARs. Sounds very much like amphetamines (and trace amines like PEA), but the article does not mention any monoamine releasing activity.

-undopaminergic


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