Psycho-Babble Medication | about biological treatments | Framed
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Re: Tardive dyskinesia

Posted by undopaminergic on March 26, 2020, at 5:03:42

In reply to Re: Tardive dyskinesia, posted by linkadge on March 25, 2020, at 16:27:38

> I have not. If I recall, you are on clozapine which has a relatively low d2 receptor occupancy. It also has 5-ht1a agonism which is hypothesized to inhibit the development of TD.
> Linkadge

I'm actually on 3 anti-psychotics, including clozapine, sulpiride, and cariprazine. Additionally, trimipramine has substantial anti-psychotic activity.

It's crazy, yes, given how diminutive my psychotic symptoms are.

The 5-HT1A agonism was news to me. I also read that it increases dopamine release in the prefrontal cortex in part due to this action.





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