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Re: Caplyta

Posted by undopaminergic on January 19, 2020, at 8:40:24

In reply to Re: Caplyta, posted by Lamdage22 on January 19, 2020, at 4:22:18

> I wonder if I would get serotonin Syndrome. I am on Venlafaxine 37.5 and Trazodone 75. If it wasn't for that fact, I'd try it in a heartbeat. No weight gain, right? But it could have sexual sides because it is a Serotonin Reuptake Inhibitor.

Your dose of both these drugs is so low that I wouldn't worry the slightest about serotonin syndrome. In any case, life-threatening serotonin toxicity (ST) is exceedingly rare with only reuptake inhibitors. As a precaution, though, it may be a good idea to have some cyproheptadine (Periactin) (CHD) at hand as an antidote. Actually, now it occurs to me that trazodone blocks serotonin 5-HT2A receptors, which is the same action through which CHD works as an antidote to ST.





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