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Re: Nardil success/restart Lamdage22

Posted by undopaminergic on January 19, 2020, at 8:06:54

In reply to Re: Nardil success/restart, posted by Lamdage22 on January 19, 2020, at 4:05:18

> I went hypertensive on much more than 105. But I heard that higher dosages are more GABAergic, but no more MAOI inhibition.

Right. You cannot inhibit more than 100% of MAO. Or alternatively, maybe the dose-response curve for MAO-inhibition flattens before reaching 100%, but either way, there is a ceiling.

> I don't know. It puzzles me how the same drug won't work after taking a break.

It is because the brain has changed. Some receptors downregulated, some upregulated, and maybe something else too, such as a bit of apoptosis, or the opposite, such as nerve growth.





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