Posted by greg rizzo on January 16, 2020, at 15:34:06
In reply to Nardil success/restart, posted by Jadde on January 16, 2020, at 9:43:41
Sorry to hear Nardil is giving you problems. I've been on it since 1988 so I too have had my ups and downs I currently take 90 mg & it takes exactly 4 weeks to kivk in again after I've off it. You've probably heard Nardil was much more effe ctive until 2003 when the manufacting rights wewe sold to Pfizer. Pfizer has now discontinued manufacturing it. That's how much they give a damn about us.
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Here is the trial I am undertaking to restore Nardil to it'e pre 2003 efficacy:
Facts we already know:
1.New nardil is too quickly metabolized and excreted mainly due to the acidic nature of the stomach. (or so the literature states). It is theorized that the carnuba wax coating on the old Nardil prevented this from happening. Again this is theorized.
So what can we do about the new lack of efficacy us old-timers notice compared to the old nardil formula.
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Here's what I'm trying:
1.Encasing nardil tablets in empty enteric cellulose capsules.
2. Taking Bioperine which the literature says increases absorpyion and bioavailability of medication.
3. Taking an antacid hopefully to reduce the acidic nature of the stomach.
4. At Dr. Bob's (Administer of this site)suggestion ,I take invert sugar-- honey) and a sip of alcohol. Dr. Bob's comments--"The best excipients to aid absorption into the small intestine are sugar invert (a.k.a. honey) and ethanol (alcohol). Sugar is quite good, but absorbtion, though high, is relatively slow.
As far as absorption into the small intestine, NOTHING beats alcohol. It's rate and level of absorption by the small intestine is extremely high. Obviously, I don't mean gulp shots of tequila, I'm talking mere drops of alcohol.
Therefore mixing nardil with either honey or alcohol has been much more effective."---------Been trying this trial for only 10 days. Too soon to tell if it will increase efficacy.
poster:greg rizzo
thread:1107965
URL: http://www.dr-bob.org/babble/20200104/msgs/1107968.html