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Re: Pindolol (a beta-blocker) can alleviate depression

Posted by undopaminergic on January 8, 2020, at 2:58:14

In reply to Re: Pindolol (a beta-blocker) can alleviate depression Hugh, posted by phidippus on December 11, 2019, at 18:53:22

> Pindolol is a potent 5ht1a partial agonist and is also useful in the treatment of OCD.
>

Antagonist actually. It is thought to disinhibit serotonin release by blocking serotonergic autoreceptors located presynaptically. Usually with autoreceptor antagonists, the dose must be kept low, to avoid also blocking postsynaptic receptors.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20200104/msgs/1107742.html