Posted by undopaminergic on December 19, 2019, at 7:18:55
In reply to Re: Original MAOI vs TCA studies » sigismund, posted by linkadge on December 18, 2019, at 16:24:38
> I would second that. I found trimipramine better than mirtazapine. On paper, they should be similar. Trimipramine had more of an anti-anhedonic effect. Not sure why.
>
> LinkadgeI wouldn't go so far as to call it anti-anhedonic, but I've noticed some anti-apathetic effects myself, especially at the start, with a dose of only 25 mg. I found it gave me more of a choice over whether to be active or rest.
I notice less with 50 mg, which I've been on for months now.
I think these effects may be related to the fact that it is a histamine H2-receptor antagonist. See the studies of famotidine in schizophrenia.
-undopaminergic
poster:undopaminergic
thread:1107284
URL: http://www.dr-bob.org/babble/20191019/msgs/1107326.html