Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Venlafaxine vs. Duloxetine more stimulating? linkadge

Posted by undopaminergic on December 9, 2019, at 10:34:23

In reply to Re: Venlafaxine vs. Duloxetine more stimulating? beckett2, posted by linkadge on September 24, 2019, at 18:29:44

> I have not taken Cymbalta. I was possibly considering as being more noradrenergic than Effexor (at least on paper).
>
> Linkadge

One stategy is to adjust serotonin and noradrenaline reuptake inhibitions independently of each other.

Eg. titrate sertraline (or escitalopram, etc.) to find the most suitable dose. Do the same with reboxetine (or atomoxetine or nortriptyline).

Warning, the -oxetines may cause depersonalisation. It is known that atomoxetine is a kappa-opioid agonist. However, that may be true of reboxetine as well, because several people, including myself, have experienced depersonalisation from the use of this drug. In my case, this symptom did not reverse upon cessation of reboxetine. I still suffer from it more than 15 years later. Thus, your safest bet is nortriptyline, but this drug has other side effects (eg. antihistamine) and it is less noradrenaline-selective.

-undopaminergic


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:undopaminergic thread:1106216
URL: http://www.dr-bob.org/babble/20191019/msgs/1107123.html