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Re: Akathisia and outcome

Posted by binbash on September 25, 2019, at 5:01:15

In reply to Akathisia and outcome, posted by Alexey on December 21, 2017, at 12:18:00


I think I have something very similar to you Alexey. I have been struggling with health problems for several years. During this time, I tried dozens of drugs and at best, they did not help me and after many I felt even worse.
Finally, after many attempts, I came across Quetiapine and It worked. My concentration returned, I calmed down and felt almost normal. No drug has given me such relief as Quetiapine (with the exception of Ondansetron).
The problem is that if, for example, I take a dose at a different time than usual or I forget to take a dose at all or make a mistake and take a different dose than usual, the drug stops working and I need to increase the dose to start working again. In this way, for those few years I have reached a dose of 3050mg of Quetiapine daily.

The scheme is the same not only for Quetiapine but also for other drugs, for example Mianserin, Clozapine, Ondansetron, Tranylcypromine (Parnate) and even Amphetamine.

Is it possible that my body somehow remembers the substance and blocks its action permanently? If so, how is this happening?

Is it possible that this problem has something to do with the blood-brain barrier or immune system?




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