Posted by TH on July 22, 2019, at 5:48:02
In reply to Re: HELP PARNATE POOP OUT, posted by rose45 on July 22, 2019, at 4:47:17
When the medication was initially working at 30mg, I didn't have any real afternoon sleepiness at all. I'm not sure whether it's an effect of the increase to 40mg or from the loss of effectiveness.
Although I have found myself more active and motivated, I have never found it activating. I generally felt more at peace internally, which I would describe as a "grounding" feeling. I would agree to the sense of becoming less sensitive, but for the relief it brought it was well worth it. Ever since it ceased to work, despite maintaining the dose, it has definitely been very sedating.
I am reasonably confident that I would be able to tolerate an increased dose if that is the outcome of the psychiatrist appointment. If it does help, it may indicate the potential for a higher dose to help if you are able to tolerate it.
Have you considered the (possibly temporary) addition of a sedating antidepressant such as amitriptyline to help with riding out the rough period of increasing the dosage? While this particular combination is often claimed to be dangerous, this is incorrect: https://psychotropical.com/overview_maoi_and_tca_interactions/
Am I correct in understanding that you are also taking Mercury Pharma brand Parnate, and that this trouble began in early 2019? Because this would be around the time that my medication also began to fail. I would be very interested in finding out if anyone else had developed similar problems around the same time. I may ask around at various medication forums to see if anyone else using Mercury Parnate has had a similar problem recently.
The International MAOI Expert Group I was referring to is the same one set up by Dr. Gillman.
poster:TH
thread:1105323
URL: http://www.dr-bob.org/babble/20190513/msgs/1105360.html