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Re: Anticholinergics associated with dementia

Posted by PeterMartin on June 26, 2019, at 0:51:51

In reply to Anticholinergics associated with dementia, posted by Stargazer2 on June 26, 2019, at 0:29:35

Yea I saw that article that's making that rounds but it's causal. Maybe people who are more prone to dementia seek help for other psych issues and thus get put on psych meds that often affect ACh.

Also Tricyclic antidepressants are said to be the most Anticholinergic meds there are. This 2016 study says Tricyclics actually reduce the risk of dementia: https://www.ncbi.nlm.nih.gov/pubmed/26845268

The other types up it slightly but point is it's more likely that we really just don't know at the moment. For everything you take that might increase the risk there might be obscure sh*t you're taking the lowers the risk.

I mean I currently take Metformin and have been for over a year to offset MAOi weight gain. Some studies have shown that reduces the risk of dementia (although other conflict that). Lithium....some studies find it reduces the risk of dementia....

We just need to hope that dementia itself is understood better before we reach an age where it starts to take hold. On a long enough timeline I think most humans reach the point where their brain dont' function as they used to. Hopefully there'll be better medicines in the future.

But by all means if you're taking an Anticholinergic that's unnecessary maybe this would be a reason to talk to your doc.....


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poster:PeterMartin thread:1104979
URL: http://www.dr-bob.org/babble/20190513/msgs/1104980.html