Posted by linkadge on April 5, 2019, at 15:31:40
Earlier this week, there was a story about a Scottish woman with a genetic variant that has resulted in a virtually pain and anxiety free life. I posted the link below. I looked up the variant, and interestingly it was related to the endocannabinoid system. Having used medical marijuana for close to a year now, I was naturally interested. After having taken several psychiatric meds, I found medical cannabis has virtually eliminated treatment resistant GAD.
The woman had a knockout for an enzyme called FAAH. FAAH metabolizes endocannabinoids like anandamide and 2-AG. Because of the genetic variant, the woman had dramatically elevated levels of these endocannabinoids and much reduced pain and anxiety perception. We don't (yet) have FAAH inhibitors available as medications. Some supplements purportedly inhibit it (to a low extent) (i.e. cocoa, Maca). However, I am keeping my eye out for trends in this potentially promising target. What I've noticed about cannabis, is that it relieves anxiety without inducing insomnia or apathy. It also (honestly) feels like it is helping be better "get over" the fears, rather than suppressing them (as the SSRIs feel like they do with me).Thoughts?
https://www.sciencedaily.com/releases/2019/03/190327203450.htm
Linkadge
poster:linkadge
thread:1103867
URL: http://www.dr-bob.org/babble/20190206/msgs/1103867.html