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Re: Brain neuroplasticity?

Posted by linkadge on April 5, 2019, at 15:21:16

In reply to Brain neuroplasticity?, posted by SLS on April 5, 2019, at 12:17:38

Some, but not all psychiatric medications (or treatments) alter plasticity in one way or another. Exercise, environmental / social enrichment, fasting and nutritional interventions can also positively improve plasticity.

I wish I could point to one medication that stands out above the rest in terms of improving brain placticity, but I don't think we have direct data on this. In terms of psychiatric disorders, a few thoughts come to mind.

1) Getting the best sleep. Sleep is critical for brain rejuviation (stem cell rejuvination). If your disorder or medications are messing with sleep, then your brain could well be negatively impacted. Improve sleep quality #1.


2) Reducing stress (cortisol and inflamation). Both cortisol and brain inflamation are negative moduators of neuroplacticity. In mice, blocking cortisol alone enhances neurogenesis. Hippocampal inflammation directly supresses neurogenesis. Some meds are better than others at controlling inflamation / cortisol

3) Ensure adequate vitamin / mineral intake (with focus on folic acid / b vitamins, magnesium and zinc)


4) Reduce unncessary carbs, stabilize blood sugar, and improve insulin sensitivety. The brain is one of the first organs to be come insulin resistant, resulting in diminished brain function (and likely placiticty).

5) Introduce postitive regulators of neuroplacticty. Ie. folic acid, DHA, fasting, exercise, blueberries, cococa, turmeric, lithium, 5-ht1a agonists, 5-ht2c antagonists...


Linkadge



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