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Re: which antipsychotics can make you calm?

Posted by Christ_empowered on April 5, 2019, at 9:13:54

In reply to Re: which antipsychotics can make you calm?, posted by farshad on April 5, 2019, at 5:18:25

aripiprazole is somewhat less toxic than many others. low dose amisulpride might be helpful (?), since it can boost mood a bit...but i think that effect diminishes, over time.

low dose risperidone is not terrible, but prolactin elevation can be an issue. wasn't a fan of low dose olanzapine myself, but some people swear by it.

amoxapine is a tca that does double duty as a tranquilizer. at sufficient doses, it -might- act as an 'atypical' antipsychotic, with pronounced effects on mood and anxiety, as one would expect from a drug marketed for depression.

a fairly standard mix is a sedative+antipsychotic. back in the 60s, when combo pills were 'in,' they made some with fixed amounts of barbiturates+antipsychotic, meprobamate+antipsychotic, etc. anyway..

point there is that a gaba-acting sedative (benzodiazepine, lyrica, gabapentin all come to mind) plus an antipsychotic provide 2 forms of sedation. the sedative helps soothe akathisia and such from the antipsychotic, while also allowing for a lower dose. the antipsychotic, meanwhile, does its job and that way a lower dose of the sedative can be used. something like that, anyway.

hope this helps. :-)


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