Posted by SLS on January 9, 2019, at 22:09:40
In reply to Re: Fish oil: Maybe not so effective after all. » SLS, posted by linkadge on January 8, 2019, at 16:52:29
> I think the totality of evidence still suggests a positive benefit. Perhaps not necessarily as a sole agent, but for augmentation (i.e. like lithium augmentation).
You are probably right.
> There is some evidence that Omega3 can still reduce inflammation, even in cases where it doesn't improve mood.Yes. I just read that.
> Also, I find some of the evidence for bipolar more interesting. Omega 3, biochemically, works more like a mood stabilizer than it does an antidepressant.
Perhaps that's why some people here describe feeling more depressed on fish oil. I wonder if pure EPA would affect these people differently.
> For example, most antidepressants increase PKC, whereas mood stabilizers and O3 reduce it.
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>
> I, personally, find DHA very helpful. It helps most with pain and generalized overstimulation (sensitivity to light and sound). It also seems to stabilize my mood. It feels like valproate with a bit more antidepressant / procognitive effect.
>
> LinkadgeThanks for the info.
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