Posted by SLS on December 9, 2018, at 9:09:27
In reply to Parnate mini heart attack., posted by Sylvia77 on December 6, 2018, at 1:52:48
Hi.
> I was briefly on this site in 2007 when I was struggling with debilitating depression and the insomnia of starting parnate. It was my last resort as my depression was treatment-resistant and I had tried nearly everything. I found this community to be extremely helpful as my Doc (who is now retired) had never prescribed an MAOI. Once I acclimated to the drug it worked beautifully! for 11 years I have been Depression (w a capital D) free. Then the day before Thanksgiving I had a cardiac situation. Unprecedented chest pain, difficulty breathing, nausea, cold sweats, and pain in my jaw, back, neck and arms. Within an hour I had rounded a corner though and was painting by bathroom. The next day I told my sister about it and she convinced me to go to the ER, but I was embarrassed because I no longer had symptoms. Through a blood test they discovered elevated Troponin - a molecule that is released upon injury to the heart. It was on the low end .38 and they don't quantify a full-on heart attack unless it's at least .41. Regardless, I spend 3 days in the cardiac unit as they monitored my heart, as well as conducted a echocardiogram and CAT scan. Thankfully the tests determined that my heart is apparently in perfect health. No damage and no calcium/plaque in my arteries. I am a 40 yr old female, do not eat meat, exercise regularly, and have low cholesterol BUT I do take 40 mg of Parnate daily. I know literally no one who has ever taken or prescribed Parnate, so this community is my only hope. Obviously I do not want to stop taking a medication that has no doubt saved my life, and as you know there is no easy way to conduct a test as it would take me months to titrate off of it, and relapsing into Depression is not an option for me.
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> I also take .15mg of Florinef for Neurally Mediated Hypotension / Fibromyalgia which has been immensely effective for chronic pain and fatigue. I feel like I've found a cocktail that has stabilized me for years, but can't deny either/both of these meds may have played a role in my mini heart attack.
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> What do you think? I welcome any thoughts any of you may have based on your own experience and expertise.I have no expertise, but I do have some experience using Parnate. Hypertensive events, whether precipitated by tyramine ingestion or occuring spontaneously, does place an extra load on the heart. Heart palpitations are not uncommon as a side effect, but are not usually the results of serious alterations in heart function. That being said there have been reports of myocardial infarction in association with Parnate. I doubt that it happens often, though. I should think that it would see more of it otherwise.
This article deals with Parnate use, mycardial infarction, and troponin release.
https://www.ncbi.nlm.nih.gov/pubmed/30083815
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1102302
URL: http://www.dr-bob.org/babble/20181024/msgs/1102345.html