Posted by cadburyhesychasm on October 8, 2018, at 4:58:45
In reply to Anyway to decrease Substance P indirctly/naturally, posted by cadburyhesychasm on October 2, 2018, at 7:03:54
I read Gabapentin decreases Substance P due to it's action on ion calcium channels. Anyway I have started Gabapentin at a dose of 300mg tid. because I wanted fo get rid of Risp and though it is crappy as an antimanic it seems to be highly effective for agitation aggression in certain populations and I believe it might help me, I think my symptoms of mainly rage and depression and continuous explosive irritability since 13 years is probably a result of early brain damage and I'm quite convinced about that. It is not purely psych bipolar I think because it is just extreme rage and depression all the time. I had the option of adding Trileptal to Lithium but because of how high dose carbamazepine and aptiom were ineffective I chose gabapentin.
One of the nice things I noted About GBP is that I get a little teary in the eyes. It is because of that I believe it might work, one of the main symptoms is that during rage and nonepisodic constant irritability when treatment is only partially effective or not at all I lose all feelings and become full of only hostility.
I hope I can discontinue Risp except last time I got high blood pressure possibly from Gabapentin hoping if was a fluke.
I have an organic ginger root supplement on the way. I will start it at about 2gm a day. I read dosage should not exceed 10gms.
poster:cadburyhesychasm
thread:1101160
URL: http://www.dr-bob.org/babble/20180728/msgs/1101240.html