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Re: My Genetic Test results re AD's - discussion

Posted by linkadge on August 31, 2018, at 16:35:47

In reply to My Genetic Test results re AD's - discussion, posted by Mtom on August 29, 2018, at 15:58:21

This basically means that you may have higher levels of drugs that are metabolized by CYP2D6.

When they say that this means "possibly higher levels of TD or side effects" this is nonsense. Why? Because you simply lower the dose.

If somebody with fast metabolism and somebody with slow metabolism both take the same dose, the one with slow metabolism will have higher blood levels. This just means that the one with slower metabolism can get away with a lower dose.

They key is to start with lower doses, and increase slowly to see if the drug works, and if you can tollerate the side effects. Don't pay attention to a "theraputic dose", because its a "theraputic blood level" that matters.

Linkadge


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