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Re: Let's talk about combing SSRIs and TCAs » TriedEveryMedication

Posted by ed_uk2010 on June 26, 2018, at 18:37:16

In reply to Re: Let's talk about combing SSRIs and TCAs » ed_uk2010, posted by TriedEveryMedication on June 25, 2018, at 14:46:19

Hi,

>my blood levels of desipramine have been very low.

In that case, if you need to increase desipramine to help relieve depression, be guided by:

1. Typical desipramine adverse effects such as elevated heart rate (can easily monitor this), very excessive sweating etc. If these appear, consider reducing desipramine again.

2. Your ECG/EKG. Consider checking after dose increases. Can measure the QTc interval and other cardiac indices.

Increasing the dose in small steps is advisable.


 

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