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Re: going off of Abilify » Noa

Posted by SLS on May 23, 2018, at 20:00:54

In reply to Re: going off of Abilify » ed_uk2010, posted by Noa on May 23, 2018, at 14:07:32

Hi, Noa.

It's nice to see you again.

I'm afraid I can't guide you at this juncture. First of all, I switched directly from Abilify to Saphris - mainly because of weight gain and high triglycerides produced by Abilify. Any rebound depression resulting from Abilify discontinuation might be masked by Saphris. A friend of mine has tried to discontinue Abilify a few times, but found herself wanting to restart it because of the appearance of anxiety after two weeks. I suffered a hell of a crash into depression yesterday. It might not be an unrelated coincidence that it occurred at the two-week mark post-discontinuation.

You might want to taper Abilify slowly and methodically. Abilify has a half-life of 72 hours or more. You can work your way down such that you can space your doses 2-3 days apart at the end of the taper period. If anxiety should appear, you could use an anxiolytic as a temporary bridge to help you get through withdrawal. Are there any benzodiazepines that you had success with in the past? I would suggest looking at Ativan or Xanax XR.

Saphris has some interesting antidepressant properties.

What are you taking now?

Maybe you can help me. Have you ever taken Trintellix (vortioxetine)? If so, how did you react to it?

I hope you don't have a difficult time discontinuing Abilify.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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