Posted by PeterMartin on April 23, 2018, at 21:44:31
Maybe of interest to some. Seems like a novel method of action so perhaps the analogs (if developed for oral consumption) might be helpful in time.
NDA Submitted for Postpartum Depression Treatment Brexanolone
Brexanolone is a proprietary allosteric modulator of both synaptic and extrasynaptic GABAA receptors. The NDA is supported by 3 multicenter, randomized, double-blind, placebo-controlled trials (Study 202A, Study 202B, and Study 202C) in women with moderate to severe PPD who were screened ≤6 months after giving birth.
poster:PeterMartin
thread:1098323
URL: http://www.dr-bob.org/babble/20180331/msgs/1098323.html