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Re: Why is alcohol the only thing that helps me? » Prefect

Posted by linkadge on April 7, 2018, at 13:56:24

In reply to Re: Why is alcohol the only thing that helps me? » linkadge, posted by Prefect on April 7, 2018, at 12:11:54

>I think you may be onto something about reward >pathways. This is why I'm considering either low >dose naltrexone to raise my opioid levels or low >dose abilify to balance dopamine levels. What's >your thoughts on this?

Hmm. I like to use the 'feel good' test. If the drug makes you feel better, take it. Naltrexone or abilify may help (I have not taken either, so I have no sense of the feel).

I read one study in which the AD effect of ketamine was associated with a rapid activation of the reward pathways in the brain. It seemed to work in mice to quickly normalize activity in this region (in patients where there was underactivity).

I'm not advocating using any drug willy-nilly to feel good (as there can be pitfalls). I just know from my own case, that when I get really depressed I don't feel anything and don't want to do anything. SSRIs don't seem to help this (or even make it worse).

Linkadge


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