Re: CB1 agonism 5-ht1a autoreceptor desensitization

Posted by SLS on March 30, 2018, at 23:31:13

In reply to CB1 agonism 5-ht1a autoreceptor desensitization, posted by linkadge on March 30, 2018, at 18:18:54

> https://www.ncbi.nlm.nih.gov/pubmed/22133541
>
> The sustained activation of monoaminergic neurons by cannabinoid drugs can also be related to changes in the function of presynaptic inhibitory α(2)-adrenoceptors or 5-HT(1A) receptors (autoreceptors and heteroreceptors), whose sensitivity is downregulated or upregulated upon chronic CB(1) agonist exposure.
How does this translate clinically?

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
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CB1 agonism 5-ht1a autoreceptor desensitization linkadge 3/30/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization SLS 3/30/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization » SLS linkadge 3/31/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization bleauberry 4/9/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization Lamdage22 4/10/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization Prefect 4/15/18
Re: CB1 agonism 5-ht1a autoreceptor desensitization Lamdage22 4/16/18

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